| Statistic | Value | Details |
| Biggest win by Melbourne City FC | 4 goals | 31/10/2015 Perth Glory 0-4 Melbourne City FC |
| 20/12/2015 Melbourne City FC 4-0 Perth Glory | ||
| 13/02/2022 Perth Glory 0-4 Melbourne City FC | ||
| Biggest win by Perth Glory | 3 goals | 27/10/2017 Perth Glory 4-1 Melbourne City FC |
| 25/11/2018 Perth Glory 5-2 Melbourne City FC | ||
| Most goals scored by Melbourne City FC against Perth Glory | 4 goals | 31/10/2015 Perth Glory 0-4 Melbourne City FC |
| 20/12/2015 Melbourne City FC 4-0 Perth Glory | ||
| 13/02/2022 Perth Glory 0-4 Melbourne City FC | ||
| Most goals scored by Perth Glory against Melbourne City FC | 5 goals | 25/11/2018 Perth Glory 5-2 Melbourne City FC |
| Red cards | Lauren Barnes | 27/12/2016 Melbourne City FC 2-3 Perth Glory |
| Hattricks scored in this fixture | Millie Farrow | 9/12/2023 Melbourne City FC 1-3 Perth Glory |
| Most goals scored in this fixture | 1. 5 goals | Sam Kerr |
| 2. 3 goals | Jess Fishlock | |
| Larissa Crummer | ||
| Rachel Hill | ||
| Hannah Wilkinson | ||
| Millie Farrow |
| Season | Date | Match Type | Melbourne City FC wins | Draws | Perth Glory wins |
| 2015/16 | 31/10/2015 | League | Perth Glory 0-4 Melbourne City FC | ||
| 2015/16 | 20/12/2015 | League | Melbourne City FC 4-0 Perth Glory | ||
| 2016/17 | 27/12/2016 | League | Melbourne City FC 2-3 Perth Glory | ||
| 2016/17 | 12/02/2017 | Grand Final | Perth Glory 0-2 Melbourne City FC | ||
| 2017/18 | 27/10/2017 | League | Perth Glory 4-1 Melbourne City FC | ||
| 2017/18 | 7/01/2018 | League | Melbourne City FC 3-0 Perth Glory | ||
| 2018/19 | 25/11/2018 | League | Perth Glory 5-2 Melbourne City FC | ||
| 2019/20 | 19/12/2019 | League | Melbourne City FC 1-0 Perth Glory | ||
| 2020/21 | 19/03/2021 | League | Perth Glory 0-1 Melbourne City FC | ||
| 2020/21 | 25/03/2021 | League | Melbourne City FC 2-1 Perth Glory | ||
| 2021/22 | 13/02/2022 | League | Perth Glory 0-4 Melbourne City FC | ||
| 2022/23 | 27/12/2022 | League | Melbourne City FC 1-0 Perth Glory | ||
| 2022/23 | 26/03/2023 | League | Perth Glory 4-3 Melbourne City FC | ||
| 2023/24 | 9/12/2023 | League | Melbourne City FC 1-3 Perth Glory |